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apparent diffusion coefficient adc maps  (Bruker Corporation)


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    Bruker Corporation apparent diffusion coefficient adc maps
    A. The percentage of viable and necrotic tissue with respect to the total lesion volume. B.The evolution of vessel radius (R). C. Blood volume fraction (BVF). D. Oxygen saturation (StO 2 ) E. Signal enhancement F. Apparent diffusion <t>coefficient</t> <t>(ADC)</t> observed by MRI at D4, D7, D14, D28, and D56 after ischemic injury by malonate injection. n=5 at D4, n=13 at D7, n=8 at D14, n=8 at D28 and n=7 at D56. Data is represented by medians and IQR. *: 0.03>p>0.01, **: 0.005>p>0.001, ***: 0.0005>p>0.0001, ****: p<0.0001 vs contralateral hemisphere, paired non-parametric Mann-Whitney test.
    Apparent Diffusion Coefficient Adc Maps, supplied by Bruker Corporation, used in various techniques. Bioz Stars score: 97/100, based on 3085 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/apparent+diffusion+coefficient+maps/Diffusion/bio_rxiv__2025__10__22__684053-75-0-10
    Average 97 stars, based on 3085 article reviews
    apparent diffusion coefficient adc maps - by Bioz Stars, 2026-10
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    Images

    1) Product Images from "Multimodal Characterization and Evolution of Malonate-induced Stroke Model: Advanced MRI, Histology-Molecular Profiling"

    Article Title: Multimodal Characterization and Evolution of Malonate-induced Stroke Model: Advanced MRI, Histology-Molecular Profiling

    Journal: bioRxiv

    doi: 10.1101/2025.10.22.684053

    A. The percentage of viable and necrotic tissue with respect to the total lesion volume. B.The evolution of vessel radius (R). C. Blood volume fraction (BVF). D. Oxygen saturation (StO 2 ) E. Signal enhancement F. Apparent diffusion coefficient (ADC) observed by MRI at D4, D7, D14, D28, and D56 after ischemic injury by malonate injection. n=5 at D4, n=13 at D7, n=8 at D14, n=8 at D28 and n=7 at D56. Data is represented by medians and IQR. *: 0.03>p>0.01, **: 0.005>p>0.001, ***: 0.0005>p>0.0001, ****: p<0.0001 vs contralateral hemisphere, paired non-parametric Mann-Whitney test.
    Figure Legend Snippet: A. The percentage of viable and necrotic tissue with respect to the total lesion volume. B.The evolution of vessel radius (R). C. Blood volume fraction (BVF). D. Oxygen saturation (StO 2 ) E. Signal enhancement F. Apparent diffusion coefficient (ADC) observed by MRI at D4, D7, D14, D28, and D56 after ischemic injury by malonate injection. n=5 at D4, n=13 at D7, n=8 at D14, n=8 at D28 and n=7 at D56. Data is represented by medians and IQR. *: 0.03>p>0.01, **: 0.005>p>0.001, ***: 0.0005>p>0.0001, ****: p<0.0001 vs contralateral hemisphere, paired non-parametric Mann-Whitney test.

    Techniques Used: Diffusion-based Assay, Injection, MANN-WHITNEY

    Related Articles

    Diffusion-based Assay:

    Article Title: Characterization of edema by diffusion-weighted imaging in experimental traumatic brain injury.
    Article Snippet: ing (DWI) is a new magnetic resonance (MR) technique, which, by using additional strong magnetic field gradients, is sensitized to the random, microscopic translational motion of water protons.. Apparent diffusion coefficient (ADC) maps can be derived from a series of DWI images obtained with varying magnetic field gradients.. Recent findings in experimental cerebral ischemia models indicate that ADCs could provide earlier and more specific information about ischemic tissue damage and its characteristics of edema.

    Article Title: Migraine Mutations Increase Stroke Vulnerability by Facilitating Ischemic Depolarizations
    Article Snippet: Glutamatergic mechanisms were tested by administering MK-801 (1 mg/kg IP; Sigma, St Louis, MO) 15 minutes before filament occlusion of the middle cerebral artery (fMCAO). .. Apparent diffusion coefficient maps were acquired under isoflurane anesthesia with a 9.4-T magnetic resonance imaging (MRI) scanner (Bruker Biospin, Inc, Billerica, MA) 30 and 60 minutes after fMCAO (repetition time/echo time, 3000/27 milliseconds; b, 154 and 1294 s/mm2; in-plane resolution, 180 180 m2; slice thickness, 1 mm; number of averaging, 8). ..

    Generated:

    Article Title: Characterization of edema by diffusion-weighted imaging in experimental traumatic brain injury.
    Article Snippet: ing (DWI) is a new magnetic resonance (MR) technique, which, by using additional strong magnetic field gradients, is sensitized to the random, microscopic translational motion of water protons.. Apparent diffusion coefficient (ADC) maps can be derived from a series of DWI images obtained with varying magnetic field gradients.. Recent findings in experimental cerebral ischemia models indicate that ADCs could provide earlier and more specific information about ischemic tissue damage and its characteristics of edema.

    Magnetic Resonance Imaging:

    Article Title: Migraine Mutations Increase Stroke Vulnerability by Facilitating Ischemic Depolarizations
    Article Snippet: Glutamatergic mechanisms were tested by administering MK-801 (1 mg/kg IP; Sigma, St Louis, MO) 15 minutes before filament occlusion of the middle cerebral artery (fMCAO). .. Apparent diffusion coefficient maps were acquired under isoflurane anesthesia with a 9.4-T magnetic resonance imaging (MRI) scanner (Bruker Biospin, Inc, Billerica, MA) 30 and 60 minutes after fMCAO (repetition time/echo time, 3000/27 milliseconds; b, 154 and 1294 s/mm2; in-plane resolution, 180 180 m2; slice thickness, 1 mm; number of averaging, 8). ..



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    Image Search Results


    A. The percentage of viable and necrotic tissue with respect to the total lesion volume. B.The evolution of vessel radius (R). C. Blood volume fraction (BVF). D. Oxygen saturation (StO 2 ) E. Signal enhancement F. Apparent diffusion coefficient (ADC) observed by MRI at D4, D7, D14, D28, and D56 after ischemic injury by malonate injection. n=5 at D4, n=13 at D7, n=8 at D14, n=8 at D28 and n=7 at D56. Data is represented by medians and IQR. *: 0.03>p>0.01, **: 0.005>p>0.001, ***: 0.0005>p>0.0001, ****: p<0.0001 vs contralateral hemisphere, paired non-parametric Mann-Whitney test.

    Journal: bioRxiv

    Article Title: Multimodal Characterization and Evolution of Malonate-induced Stroke Model: Advanced MRI, Histology-Molecular Profiling

    doi: 10.1101/2025.10.22.684053

    Figure Lengend Snippet: A. The percentage of viable and necrotic tissue with respect to the total lesion volume. B.The evolution of vessel radius (R). C. Blood volume fraction (BVF). D. Oxygen saturation (StO 2 ) E. Signal enhancement F. Apparent diffusion coefficient (ADC) observed by MRI at D4, D7, D14, D28, and D56 after ischemic injury by malonate injection. n=5 at D4, n=13 at D7, n=8 at D14, n=8 at D28 and n=7 at D56. Data is represented by medians and IQR. *: 0.03>p>0.01, **: 0.005>p>0.001, ***: 0.0005>p>0.0001, ****: p<0.0001 vs contralateral hemisphere, paired non-parametric Mann-Whitney test.

    Article Snippet: Apparent diffusion coefficient (ADC) maps were automatically computed on the Bruker scanner as the means of the ADCs observed in each of three orthogonal directions.

    Techniques: Diffusion-based Assay, Injection, MANN-WHITNEY

    FIGURE 2 (A) Representative images obtained in one rat at 3 h following the MCAo. The ADC map depicts the core of ischemia (arrow). The time-to-peak map reveals a larger zone of hypoperfusion (arrow). The penumbra was delineated as the mismatch between perfusion and diffusion abnormalities (hatched purple). The StO2-MRI map shows the area with reduced oxygen saturation (arrow). [18F]-FMISO-PET delineates the hypoxic area with increased retention of [18F]-FMISO (arrow). The T2-W image, acquired 24 h after the MCAo, shows the consolidated lesion (arrow). (B) Evolution of ADC-defined lesion volumes. The lesion demonstrable at 15 min expanded at 3 h, and even more so at 24 h following the MCAo. **p < 0.01; ***p < 0.001; ANOVA with repeated measures followed by Tukey's post hoc test. The boxes define the interquartile range; the solid horizontal line the median, and the whiskers represent the minimal and maximal values. (C) Volumes of brain compartments at 3 h following the MCAo. Time-to-peak (TTP): tissue volume with decreased perfusion; Penumbra: tissue with PWI/DWI mismatch; StO2-MRI: tissue that displays a decrease in oxygen saturation; [18F]-FMISO-PET: tissue volume that shows an increased retention of [18F]-FMISO. The boxes define the interquartile range; the solid horizontal line the median and the whiskers represent the minimal and maximal values. ADC, apparent diffusion coefficient; ANOVA, analysis of variance; DWI, diffusion-weighted imaging; MCAo, middle cerebral artery occlusion; PET, positron emission tomography; PWI, perfusion-weighted imaging; StO2-MRI, magnetic resonance-based imaging of brain oxygen saturation; T2-W, T2-weighted; [18F]-FMISO, 18-fluorine-fluoromisonidazole

    Journal: NMR in biomedicine

    Article Title: Magnetic resonance imaging of hypoxia in acute stroke compared with fluorine-18 fluoromisonidazole-positron emission tomography: A cross-validation study?

    doi: 10.1002/nbm.4858

    Figure Lengend Snippet: FIGURE 2 (A) Representative images obtained in one rat at 3 h following the MCAo. The ADC map depicts the core of ischemia (arrow). The time-to-peak map reveals a larger zone of hypoperfusion (arrow). The penumbra was delineated as the mismatch between perfusion and diffusion abnormalities (hatched purple). The StO2-MRI map shows the area with reduced oxygen saturation (arrow). [18F]-FMISO-PET delineates the hypoxic area with increased retention of [18F]-FMISO (arrow). The T2-W image, acquired 24 h after the MCAo, shows the consolidated lesion (arrow). (B) Evolution of ADC-defined lesion volumes. The lesion demonstrable at 15 min expanded at 3 h, and even more so at 24 h following the MCAo. **p < 0.01; ***p < 0.001; ANOVA with repeated measures followed by Tukey's post hoc test. The boxes define the interquartile range; the solid horizontal line the median, and the whiskers represent the minimal and maximal values. (C) Volumes of brain compartments at 3 h following the MCAo. Time-to-peak (TTP): tissue volume with decreased perfusion; Penumbra: tissue with PWI/DWI mismatch; StO2-MRI: tissue that displays a decrease in oxygen saturation; [18F]-FMISO-PET: tissue volume that shows an increased retention of [18F]-FMISO. The boxes define the interquartile range; the solid horizontal line the median and the whiskers represent the minimal and maximal values. ADC, apparent diffusion coefficient; ANOVA, analysis of variance; DWI, diffusion-weighted imaging; MCAo, middle cerebral artery occlusion; PET, positron emission tomography; PWI, perfusion-weighted imaging; StO2-MRI, magnetic resonance-based imaging of brain oxygen saturation; T2-W, T2-weighted; [18F]-FMISO, 18-fluorine-fluoromisonidazole

    Article Snippet: The following parameters were employed: resolution = 0.3 x 0.3 x 1.5 mm, FOV = 31.5 x 15 x 15 mm; TR/TE = 3000/46.4 ms; b-values: 0 and 1000 s/mm2; 30 directions; number of experiments (NEX) = 3; and acquisi- tion time: 5 min 15 s. Apparent diffusion coefficient (ADC) maps were then generated with PV 5.1 software (Bruker).

    Techniques: Diffusion-based Assay, Imaging, Positron Emission Tomography, Magnetic Resonance Imaging

    FIGURE 5 Representative images of StO2-MRI, [18F]-FMISO-PET, and the superimposition of both abnormalities on the ADC image for each animal. StO2-MRI abnormality is delinated in yellow and [18F]-FMISO-PET abnormality in green. ADC, apparent diffusion coefficient; [18F]-FMISO, 18-fluorine-fluoromisonidazole; PET, positron emission tomography; StO2-MRI, magnetic resonance-based imaging of brain oxygen saturation; SUV, standardized uptake value

    Journal: NMR in biomedicine

    Article Title: Magnetic resonance imaging of hypoxia in acute stroke compared with fluorine-18 fluoromisonidazole-positron emission tomography: A cross-validation study?

    doi: 10.1002/nbm.4858

    Figure Lengend Snippet: FIGURE 5 Representative images of StO2-MRI, [18F]-FMISO-PET, and the superimposition of both abnormalities on the ADC image for each animal. StO2-MRI abnormality is delinated in yellow and [18F]-FMISO-PET abnormality in green. ADC, apparent diffusion coefficient; [18F]-FMISO, 18-fluorine-fluoromisonidazole; PET, positron emission tomography; StO2-MRI, magnetic resonance-based imaging of brain oxygen saturation; SUV, standardized uptake value

    Article Snippet: The following parameters were employed: resolution = 0.3 x 0.3 x 1.5 mm, FOV = 31.5 x 15 x 15 mm; TR/TE = 3000/46.4 ms; b-values: 0 and 1000 s/mm2; 30 directions; number of experiments (NEX) = 3; and acquisi- tion time: 5 min 15 s. Apparent diffusion coefficient (ADC) maps were then generated with PV 5.1 software (Bruker).

    Techniques: Diffusion-based Assay, Positron Emission Tomography, Magnetic Resonance Imaging